I'm Wouter Bulten -- COO & CPO at Aiosyn, where we're bringing AI to clinical pathology practice. I hold a PhD in computational pathology and have spent over 15 years at the intersection of artificial intelligence, healthcare, and product development. This page traces that journey, from early software engineering through academic research to startup leadership.
Work Experience
- Feb 2024 - Present
COO & CPO
Aiosyn
Leading operations and product strategy at Aiosyn, an AI startup transforming clinical pathology. Responsible for bridging cutting-edge AI research with regulatory-compliant medical device development, guiding the team from research prototypes to products used by pathologists.
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Aug 2021 - Jan 2024Chief Innovation Officer (CIO)
Aiosyn
Joined Aiosyn as its first non-founding team member to build the innovation pipeline. Established the product development process, led regulatory strategy for CE-IVDR compliance, and grew the technical team from a research lab into a product organization.
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May 2021 - Aug 2021Postdoctoral Researcher
Radboud University Medical Center
Completed research projects following my PhD defense, including follow-up analysis on the PANDA Challenge results and preparation of the Nature Medicine publication.
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Apr 2017 - Apr 2021PhD Candidate
Radboud University Medical Center
Researched deep learning methods for improved diagnostics in prostate cancer pathology. Organized the PANDA Challenge in collaboration with Google Health and the Karolinska Institute -- one of the largest medical AI competitions. Published in Nature Medicine and The Lancet Oncology.
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Sept 2009 - Aug 2021Freelance Software Developer
OuterHills
Built web applications and software solutions for clients ranging from small businesses to large organizations. Maintained a freelance practice alongside academic work, keeping engineering skills sharp and grounded in real-world delivery.
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Apr 2016 - Mar 2017Data Scientist
123test & TestingTalents
Applied data science and machine learning to psychometric testing products, working on recommendation algorithms and test validation at scale.
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Feb 2011 - Mar 2016Software Developer
123test & TestingTalents
Full-stack development on high-traffic psychometric testing platforms. Built features serving millions of users, gaining early experience in scaling web applications.
Key Publications
Artificial intelligence for diagnosis and Gleason grading of prostate cancer: the PANDA challenge
Bulten, W., Kartasalo, K., Chen, PH.C. et al.
Nature Medicine, 2022
Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study
W. Bulten, et al.
The Lancet Oncology, 2020
Artificial intelligence assistance significantly improves Gleason grading of prostate biopsies by pathologists
W. Bulten, et al.
Modern Pathology, 2021
Education
- Ongoing
Medical Device Training
Regulatory and quality training including ISO 13485 (Quality Management Systems), CE-IVDR (EU In Vitro Diagnostic Regulation), ISO 27001 (Information Security Management), and ISO 14971 (Risk Management for Medical Devices).
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Mar 2017 - Jan 2022PhD in Computational Pathology & AI
Radboud University
Research on deep learning methods for improved prostate cancer diagnostics. Organized the PANDA Challenge. Published in Nature Medicine and The Lancet Oncology.
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Sept 2012 - Aug 2015MSc in Artificial Intelligence (Cum Laude)
Radboud University
Thesis on indoor localisation of devices and users, published at IEEE IoTDI 2016.
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Sept 2009 - Aug 2012BSc in Artificial Intelligence (Cum Laude)
Radboud University
Thesis on decentralised trust ecosystems, published at BNAIC 2012.